Senior Scientist

Job Locations US-MA-Lexington
Posted Date 7 months ago(7/10/2017 12:01 PM)


Agenus (Lexington, MA) is seeking a highly talented, innovative, and motivated scientist to join our Preclinical Research Group. The selected candidate will work as part of an integrated research team focused on discovering and validating novel immunotherapeutics. 


The successful candidate is expected to work independently to design, execute, and interpret experiments. These experiments will contribute to the team's effort to create more potent immunotherapies. The candidate is expected to be a visible and vital member of a highly collaborative research environment within Agenus and with our internal and external partners.  The candidate will have strong supervisory expertise and contribute to program development and prioritization.


The incumbent will be expected to design, execute and analyze complex studies and provide leadership within program.  Incumbent will work with others in Immune Education group in a collaborative atmosphere. This will require broad knowledge of current concepts in cancer immunology and associated approaches.  Individual will present research plans and findings to Immune Education group and share expertise with other scientists.  


Additional Responsibilities:


  • Supervise and train Research Associate(s) and Scientists.
  • Use strong written and oral communication skills to interact with other Agenus scientists and external collaborators.
  • Read and analyze current scientific literature and integrate knowledge to propose new approaches and areas of study.
  • Provide critical guidance for platform evaluation and prioritization of potential targets.
  • Provide leadership for platform optimization.
  • Contribute to intellectual property submissions.



  • PhD, MD or equivalent with strong research background in immunology, preferably tumor immunology.
  • Minimum 5 years post-doctoral research experience with evidence of success, including strong publication record, patent submission expertise, and experience presenting data at national and international conferences.   
  • Proven expertise to independently initiate and drive research projects must be evident.
  • Technical skills to include:
  • Expansion of peptide-specific T cells from diverse sources.
  • T cell function assays that validate vaccine and CPM therapies
  • Strong expertise in flow cytometry (>5 color), cell-based assays and small animal models required
  • Functional analyses of T cells using multi-parametric analysis
  • Strong knowledge of immune monitoring assays
  • Experience with cancer vaccines preferred


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